Interactions of chitosan/genipin hydrogels during drug delivery: a QSPR approach

A hydrogel comprised of chitosan crosslinked using the low-toxicity crosslinker genipin was prepared, and the absorption of glibenclamide by the hydrogel was investigated. Optimized structures and their molecular electrostatic potentials were calculated using the AM1 method, and the results were use...

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Bibliographic Details
Main Authors: Nancy L. Delgadillo-Armendariz, Norma A. Rangel-Vazquez, Edgar A. Marquez-Brazon, Blanca Rojas-De Gascue
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2014-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000900014&lng=en&tlng=en