Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans

Abstract This study investigated, if genetic variants in BMP2, BMP4 and SMAD6 are associated with variations in the palatal rugae pattern in humans. Dental casts and genomic DNA from 75 patients were evaluated. Each patient was classified as follows: total amount of rugae; bilateral symmetry in the...

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Main Authors: Alice Corrêa Silva-Sousa, Guido Artemio Marañón-Vásquez, Maria Bernadete Sasso Stuani, Peter Proff, Kesly Mary Ribeiro Andrades, Flares Baratto-Filho, Mírian Aiko Nakane Matsumoto, Eva Paddenberg, Erika Calvano Küchler, Christian Kirschneck
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92169-0