Host genes related to paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition.

Host genes related to paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition.

The aim of this study was to integrate human clinical, genotype, mRNA microarray and 16 S rRNA sequence data collected on 84 subjects with ileal Crohn's disease, ulcerative colitis or control patients without inflammatory bowel diseases in order to interrogate how host-microbial interactions ar...

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Bibliographic Details
Main Authors: Tianyi Zhang, Robert A DeSimone, Xiangmin Jiao, F James Rohlf, Wei Zhu, Qing Qing Gong, Steven R Hunt, Themistocles Dassopoulos, Rodney D Newberry, Erica Sodergren, George Weinstock, Charles E Robertson, Daniel N Frank, Ellen Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3374611?pdf=render

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http://europepmc.org/articles/PMC3374611?pdf=render

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