Matrix Metalloproteinase 13 Genotype in rs640198 Polymorphism Is Associated with Severe Coronary Artery Disease

Matrix Metalloproteinase 13 Genotype in rs640198 Polymorphism Is Associated with Severe Coronary Artery Disease

Atherosclerosis as a main etiopathogenetic source for coronary artery disease (CAD) development is intimately related to dynamic changes in the extracellular matrix (ECM). Elevated levels of MMP-13 have been observed in human atherosclerotic plaques which could also involve variability in MMP-13 gen...

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Bibliographic Details
Main Authors:	Anna Vašků, Jaroslav Meluzín, Jan Blahák, Vladimír Kincl, Monika Pávková Goldbergová, Jan Sitar, Filip Zlámal, Julie Bienertová-Vašků, Jiří Vítovec
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Disease Markers
Online Access:	http://dx.doi.org/10.3233/DMA-2012-0902

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