The Clinical Course of Patients with Preschool Manifestation of Type 1 Diabetes Is Independent of the HLA DR-DQ Genotype

The Clinical Course of Patients with Preschool Manifestation of Type 1 Diabetes Is Independent of the HLA DR-DQ Genotype

Introduction: Major histocompatibility complex class II genes are considered major genetic risk factors for autoimmune diabetes. We analysed Human Leukocyte Antigen (HLA) DR and DQ haplotypes in a cohort with early-onset (age < 5 years), long term type 1 diabetes (T1D) and explored their infl...

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Bibliographic Details
Main Authors: Christina Reinauer, Joachim Rosenbauer, Christina Bächle, Christian Herder, Michael Roden, Sian Ellard, Elisa De Franco, Beate Karges, Reinhard W. Holl, Jürgen Enczmann, Thomas Meissner
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Genes
Subjects:
MHC II
C-peptide
autoimmunity
human leukocyte antigen
diabetes mellitus
Online Access:http://www.mdpi.com/2073-4425/8/5/146

Internet

http://www.mdpi.com/2073-4425/8/5/146

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