Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity

Abstract Background Inflammation, oxidative stress, and apoptosis contribute to the evolution of doxorubicin (DOX)‐induced cardiotoxicity. Osteocrin (OSTN) is a novel secretory peptide mainly derived from the bone and skeletal muscle, and plays critical roles in regulating bone growth and physical e...

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Bibliographic Details
Main Authors: Can Hu, Xin Zhang, Ning Zhang, Wen‐Ying Wei, Ling‐Li Li, Zhen‐Guo Ma, Qi‐Zhu Tang
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.124