Mouse WIF1 Is Only Modified with <i>O</i>-Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Sites

Mouse WIF1 Is Only Modified with <i>O</i>-Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Sites

The Wnt Inhibitory Factor 1 (Wif1), known to inhibit Wnt signaling pathways, is composed of a WIF domain and five EGF-like domains (EGF-LDs) involved in protein interactions. Despite the presence of a potential <i>O</i>-fucosylation site in its EGF-LDs III and V, the <i>O</i>...

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Bibliographic Details
Main Authors: Florian Pennarubia, Emilie Pinault, Bilal Al Jaam, Caroline E. Brun, Abderrahman Maftah, Agnès Germot, Sébastien Legardinier
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
click chemistry
EGF-LD
<i>O</i>-fucosylation
phylogeny
Pofut1
Wif1
Online Access:https://www.mdpi.com/2218-273X/10/9/1250

Internet

https://www.mdpi.com/2218-273X/10/9/1250

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