Tolerant, Growing Cells from Nutrient Shifts Are Not Persister Cells

There is much controversy about the metabolic state of cells that are tolerant to antibiotics, known as persister cells. In this opinion piece, we offer an explanation for the discrepancy seen: some laboratories are studying metabolically active and growing cell populations (e.g., as a result of nut...

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Bibliographic Details
Main Authors: Jun-Seob Kim, Thomas K. Wood, Martin J. Blaser
Format: Article
Language:English
Published: American Society for Microbiology 2017-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00354-17