A pharmacokinetics–pharmacodynamics study of single-dose total glucosides of paeony capsule on reducing serum total bile acid in hepatic injury rats

A pharmacokinetics–pharmacodynamics study of single-dose total glucosides of paeony capsule on reducing serum total bile acid in hepatic injury rats

Context Total Glucosides of Paeony (TGP) capsule possesses various hepatoprotective activities. No study is available concerning TGP’s concentration–effect relationship on hepatoprotection. Objective To establish a pharmacokinetics–pharmacodynamics (PK-PD) modelling on TGP capsule’s hepatoprotection...

Full description

Bibliographic Details
Main Authors: Ninghua Jiang, Bohong Zheng, Yihan Feng, Lei Yin, Yuanrong Liu, Lujing Cao, Ning Zheng, Suxiang Wu, Baoyue Ding, Xuan Huang, Jeffrey Wang, Shuyu Zhan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
paeoniflorin
albiflorin
hepatoprotection
serum biomarker
effect index
tba
concentration–effect relationship
Online Access:http://dx.doi.org/10.1080/13880209.2021.1937232

Internet

http://dx.doi.org/10.1080/13880209.2021.1937232

Similar Items