Association of Tumor Budding With Immune Evasion Pathways in Primary Colorectal Cancer and Patient-Derived Xenografts

Association of Tumor Budding With Immune Evasion Pathways in Primary Colorectal Cancer and Patient-Derived Xenografts

Tumor budding has been found to be of prognostic significance for several cancers, including colorectal cancer (CRC). Additionally, the molecular classification of CRC has led to the identification of different immune microenvironments linked to distinct prognosis and therapeutic response. However,...

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Bibliographic Details
Main Authors: Silvia Guil-Luna, Rafael Mena, Carmen Navarrete-Sirvent, Laura María López-Sánchez, Karima Khouadri, Marta Toledano-Fonseca, Ana Mantrana, Ipek Guler, Carlos Villar, Cesar Díaz, Francisco Javier Medina-Fernández, Juan Rafael De la Haba-Rodríguez, Enrique Aranda, Antonio Rodríguez-Ariza
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Medicine
Subjects:
patient-derived xenografts
tumor budding
colorectal cancer
immune evasion
toll-like receptors
chemokines
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00264/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00264/full

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