Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection.

Dengue virus (DV) infection is the most prevalent mosquito-borne viral disease and its manifestation has been shown to be contributed in part by the host immune responses. In this study, pathogen recognition receptors, Toll-like receptor (TLR) 2 and TLR6 were found to be up-regulated in DV-infected...

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Bibliographic Details
Main Authors: Jincheng Chen, Mary Mah-Lee Ng, Justin Jang Hann Chu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4520596?pdf=render