Resistin directly inhibits bacterial killing in neutrophils

Abstract Background Sepsis-induced immunosuppression is a key factor contributing to the morbidity and mortality of critically ill patients, and polymorphonuclear neutrophil dysfunction is believed to be a hallmark of this immunosuppression. Circulating myeloid cells produce the cytokine resistin (R...

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Bibliographic Details
Main Authors: Lauren Miller, Kai Singbartl, Zissis C. Chroneos, Victor Ruiz-Velasco, Charles H. Lang, Anthony Bonavia
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40635-019-0257-y