Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis

Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis

Glycoconjugate-based vaccines have proved to be effective at producing long-lasting protection against numerous pathogens. Here, we describe the application of bacterial protein glycan coupling technology (PGCT) to generate a novel recombinant glycoconjugate vaccine. We demonstrate the conjugation o...

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Bibliographic Details
Main Authors: Jon Cuccui, Rebecca M. Thomas, Madeleine G. Moule, Riccardo V. D'Elia, Thomas R. Laws, Dominic C. Mills, Diane Williamson, Timothy P. Atkins, Joann L. Prior, Brendan W. Wren
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
francisella tularensis
vaccine
glycoconjugate
protein glycan coupling technology
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130002

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130002

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