Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells

Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells

Exogenous double-stranded RNAs (dsRNAs) similar to viral RNAs induce antiviral RNA silencing or RNA interference (RNAi) in plants or invertebrates, whereas interferon (IFN) response is induced through activation of virus sensor proteins including Toll like receptor 3 (TLR3) or retinoic acid-inducibl...

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Bibliographic Details
Main Authors: Tomoko Takahashi, Yuko Nakano, Koji Onomoto, Mitsutoshi Yoneyama, Kumiko Ui-Tei
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Genes
Subjects:
RNA interference
RLRs
RIG-I
LGP2
TRBP
virus sensor
dsRNA
Online Access:http://www.mdpi.com/2073-4425/9/10/511

Internet

http://www.mdpi.com/2073-4425/9/10/511

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