Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells

Diosgenin (Di), a steroidal sapogenin derived from plants, has been shown to exert anticancer effects in preclinical studies. Using Di as a starting material, various Di derivatives were designed and synthesized, aiming to discover new steroid-based antitumor agents. In this work, we synthesized sev...

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Bibliographic Details
Main Authors: Liang Xu, Dekang Xu, Ziying Li, Yu Gao, Haijun Chen
Format: Article
Language:English
Published: Beilstein-Institut 2019-09-01
Series:Beilstein Journal of Nanotechnology
Subjects:
Online Access:https://doi.org/10.3762/bjnano.10.189