Can Src protein tyrosine kinase inhibitors be combined with opioid analgesics? Src and opioid-induced tolerance, hyperalgesia and addiction

The clinical application of opioids may be accompanied by a series of adverse consequences, such as opioid tolerance, opioid-induced hyperalgesia, opioid dependence or addiction. In view of this issue, clinicians are faced with the dilemma of treating various types of pain with or without opioids. I...

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Bibliographic Details
Main Authors: Yaoyuan Li, Yanju Bao, Honggang Zheng, Yinggang Qin, Baojin Hua
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Src
OIH
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221004352