CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3

The transcription factor STAT3 regulates genes governing critical cellular processes such as proliferation, survival, and self-renewal. While STAT3 transcriptional function is activated rapidly and transiently in response to physiologic signals, through a variety of mechanisms it can become constitu...

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Bibliographic Details
Main Authors: Susana P. Egusquiaguirre, Suhu Liu, Isidora Tošić, Kevin Jiang, Sarah R. Walker, Maria Nicolais, Tzuen Yih Saw, Michael Xiang, Katarina Bartel, Erik A. Nelson, David A. Frank
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861930209X