Impacts of autophagy-inducing ingredient of areca nut on tumor cells.

Areca nut (AN) is a popular carcinogen used by about 0.6-1.2 billion people worldwide. Although AN contains apoptosis-inducing ingredients, we previously demonstrated that both AN extract (ANE) and its 30-100 kDa fraction (ANE 30-100K) predominantly induce autophagic cell death in both normal and ma...

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Main Authors: Ching-Yu Yen, Wei-Fan Chiang, Shyun-Yeu Liu, Chung-Chih Lin, Kuo-An Liao, Che-Yi Lin, Wan-Fang Hsieh, Yon-Chi Cheng, Kai-Cheng Hsu, Pin-Yen Lin, Tai-Chi Chen, I-Ling Lee, Mei-Huei Lin, Young-Chau Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4445909?pdf=render