Epigenetic‐Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease

ABSTRACT Multiple myeloma (MM) bone disease is characterized by the development of osteolytic lesions, which cause severe complications affecting the morbidity, mortality, and treatment of myeloma patients. Myeloma tumors seeded within the bone microenvironment promote hyperactivation of osteoclasts...

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Bibliographic Details
Main Authors: Juraj Adamik, G David Roodman, Deborah L Galson
Format: Article
Language:English
Published: Wiley 2019-03-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10183