Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients

Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients

Mycobacterium (M.) abscessus infections in Cystic Fibrosis (CF) patients cause a deterioration of lung function. Treatment of these multidrug-resistant pathogens is associated with severe side-effects, while frequently unsuccessful. Insight on M. abscessus genomic evolvement during chronic lung infe...

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Bibliographic Details
Main Authors: Astrid Lewin, Elisabeth Kamal, Torsten Semmler, Katja Winter, Sandra Kaiser, Hubert Schäfer, Lei Mao, Patience Eschenhagen, Claudia Grehn, Jennifer Bender, Carsten Schwarz
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
mycobacterium abscessus
mycobacteroides abscessus
nontuberculous mycobacteria
lung infection
cystic fibrosis
genomics
population structure
gene mutations
evolution
transmission
Online Access:http://dx.doi.org/10.1080/21505594.2021.1959808

Internet

http://dx.doi.org/10.1080/21505594.2021.1959808

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