Elicitation of expert prior opinion: application to the MYPAN trial in childhood polyarteritis nodosa.

<h4>Objectives</h4>Definitive sample sizes for clinical trials in rare diseases are usually infeasible. Bayesian methodology can be used to maximise what is learnt from clinical trials in these circumstances. We elicited expert prior opinion for a future Bayesian randomised controlled tr...

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Main Authors: Lisa V Hampson, John Whitehead, Despina Eleftheriou, Catrin Tudur-Smith, Rachel Jones, David Jayne, Helen Hickey, Michael W Beresford, Claudia Bracaglia, Afonso Caldas, Rolando Cimaz, Joke Dehoorne, Pavla Dolezalova, Mark Friswell, Marija Jelusic, Stephen D Marks, Neil Martin, Anne-Marie McMahon, Joachim Peitz, Annet van Royen-Kerkhof, Oguz Soylemezoglu, Paul A Brogan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0120981