Safeguard against DNA sensing: The role of TREX1 in HIV-1 infection and autoimmune diseases

Innate immune recognition is crucial for host responses against viral infections, including infection by human immunodeficiency virus 1 (HIV-1). Human cells detect such invading pathogens with a collection of pattern recognition receptors (PRRs) that activate the production of antiviral proteins, su...

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Bibliographic Details
Main Authors: Nan eYan, Maroof eHasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Microbiology
Subjects:
HIV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00193/full