Machine learning predicts nucleosome binding modes of transcription factors

Abstract Background Most transcription factors (TFs) compete with nucleosomes to gain access to their cognate binding sites. Recent studies have identified several TF-nucleosome interaction modes including end binding (EB), oriented binding, periodic binding, dyad binding, groove binding, and gyre s...

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Bibliographic Details
Main Authors: K. C. Kishan, Sridevi K. Subramanya, Rui Li, Feng Cui
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04093-9