PfClpC Is an Essential Clp Chaperone Required for Plastid Integrity and Clp Protease Stability in Plasmodium falciparum

Summary: The deadly malaria parasite Plasmodium falciparum contains a nonphotosynthetic plastid, known as the apicoplast, that functions to produce essential metabolites, and drugs that target the apicoplast are clinically effective. Several prokaryotic caseinolytic protease (Clp) genes have been id...

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Bibliographic Details
Main Authors: Anat Florentin, David W. Cobb, Jillian D. Fishburn, Michael J. Cipriano, Paul S. Kim, Manuel A. Fierro, Boris Striepen, Vasant Muralidharan
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717315449