Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation
Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these domains as well as increases in the reactive carbonyl species methylglyoxal are implicated as a pathophysio...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-04-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1177/1759091418766175 |