Expanding the Reaction Space of Linkage-Specific Sialic Acid Derivatization

The human glycome is characterized by a high degree of sialylation, affecting, amongst others, cell&#8722;cell interactions and protein half-life. An established method for the linkage isomer-specific characterization of <i>N</i>-glycan sialylation is based on the linkage-specific de...

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Bibliographic Details
Main Authors: Tamas Pongracz, Manfred Wuhrer, Noortje de Haan
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/19/3617