Lentivirus-mediated expression of glutathione peroxidase: Neuroprotection in murine models of Parkinson's disease

Reactive oxygen species are considered to contribute to the pathogenesis of Parkinson's disease (PD). In order to study viral vector-mediated overexpression of the antioxidant enzyme glutathione peroxidase (GPX) as a potential neuroprotective approach in both an in vitro and in vivo model of PD...

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Bibliographic Details
Main Authors: Jean-Luc Ridet, Jean-Charles Bensadoun, Nicole Déglon, Patrick Aebischer, Anne D. Zurn
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001695