Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

In mature neurons the centrosome no longer functions as the main microtubule organizer and it is unclear how ordered microtubule arrays are assembled. Here, the authors show that in post-mitotic neurons this process depends on non-centrosomal nucleation mediated by the protein complex augmin and the...

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Bibliographic Details
Main Authors: Carlos Sánchez-Huertas, Francisco Freixo, Ricardo Viais, Cristina Lacasa, Eduardo Soriano, Jens Lüders
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12187