TG-1: a marker for neuronal nuclei in Alzheimer's disease

TG-1: a marker for neuronal nuclei in Alzheimer's disease

TG-1 is a monoclonal antibody (mAb) raised against paired helical filaments purified from Alzheimer's Disease (AD) brain by immunoaffinity chromatography. By immunocytochemistry, TG-1 reveals abundant staining of neuronal nuclei in AD brain, but little or no staining in normal brain. TG-1 stain...

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Bibliographic Details
Main Authors: Inez Vincent, Linda A. Mattiace, Dennis W. Dickson, Michelle Rosado, Roger Katen II, Peter Davies
Format: Article
Language:English
Published: Elsevier 1994-12-01
Series:Neurobiology of Disease
Subjects:
dentate gyrus granule cells
microtubule-associated tau protein
neurofibrillary pathology
nuclear protein kinases
paired helical filaments
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996184700180

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http://www.sciencedirect.com/science/article/pii/S0969996184700180

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