Ni-hemin metal–organic framework with highly efficient peroxidase catalytic activity: toward colorimetric cancer cell detection and targeted therapeutics

Ni-hemin metal–organic framework with highly efficient peroxidase catalytic activity: toward colorimetric cancer cell detection and targeted therapeutics

Abstract Background Given the great benefits of artificial enzymes, a simple approach is proposed via assembling of Ni2+ with hemin for synthesis of Ni-hemin metal–organic-frameworks (Ni-hemin MOFs) mimic enzyme. The formation of the Ni-hemin MOFs was verified by scanning electron microscopy, Transm...

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Bibliographic Details
Main Authors: Negar Alizadeh, Abdollah Salimi, Rahman Hallaj, Fardin Fathi, Farzad Soleimani
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Nanobiotechnology
Subjects:
Ni-hemin MOF
Peroxidase activity
TMB
H2O2
MCF-7 and Caucasian gastric adenocarcinoma cancer cells
Therapeutics efficiency
Online Access:http://link.springer.com/article/10.1186/s12951-018-0421-7

Internet

http://link.springer.com/article/10.1186/s12951-018-0421-7

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