Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study

Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study

Abstract Introduction The Ts65Dn mouse is the most widely used animal model of Down syndrome (DS). Differences in autonomic regulation of heart rate variability (HRV) in individuals with DS have been hypothesized. Pharmacological studies in animal models may help us understand mechanisms underlying...

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Bibliographic Details
Main Authors: Adriano L. Roque, Mark W. Johnson, Melissa R. Stasko, Luiz C. deAbreu, Talita D. daSilva, Alberto C.S. Costa
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Physiological Reports
Subjects:
animal models
autonomic nervous system
cardiovascular system
Down syndrome
heart rate
Ts65Dn
Online Access:https://doi.org/10.14814/phy2.14486

Internet

https://doi.org/10.14814/phy2.14486

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