Herpesvirus telomerase RNA (vTR) with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

Herpesvirus telomerase RNA (vTR) with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

Telomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation...

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Bibliographic Details
Main Authors: Benedikt B Kaufer, Sina Arndt, Sascha Trapp, Nikolaus Osterrieder, Keith W Jarosinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3203187?pdf=render

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http://europepmc.org/articles/PMC3203187?pdf=render

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