Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

While SARS-CoV-2 uses angiotensin converting enzyme 2 (ACE2) as the receptor for cell entry, it is important to examine other potential interactions between the virus and other cell receptors. Based on the clinical observation of low prevalence of smoking among hospitalized COVID-19 patients, we exa...

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Bibliographic Details
Main Authors: Konstantinos Farsalinos, Elias Eliopoulos, Demetres D. Leonidas, Georgios E. Papadopoulos, Socrates Tzartos, Konstantinos Poulas
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
COVID-19
SARS-CoV-2
smoking
nicotine
nicotinic cholinergic system
inflammation
Online Access:https://www.mdpi.com/1422-0067/21/16/5807

Internet

https://www.mdpi.com/1422-0067/21/16/5807

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