Evolving Concepts in the Pathogenesis of NASH: Beyond Steatosis and Inflammation

Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis and inflammation and, in some patients, progressive fibrosis leading to cirrhosis. An understanding of the pathogenesis of NASH is still evolving but current evidence suggests multiple metabolic factors critically disrupt ho...

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Bibliographic Details
Main Authors: William Peverill, Lawrie W. Powell, Richard Skoien
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/5/8591