Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism

Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism

An intriguing target involved in several pathophysiological processes is the 18 kDa translocator protein (TSPO), of which exact functions remained elusive until now. A single nucleotide polymorphism in the <i>TSPO</i> gene influences the binding affinity of endogenous and synthetic TSPO...

Full description

Bibliographic Details
Main Authors: Neydher Berroterán-Infante, Monika Tadić, Marcus Hacker, Wolfgang Wadsak, Markus Mitterhauser
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
TSPO
rs6971 polymorphism
diazepam binding inhibitor
protoporphyrin IX
disulfiram
binding affinity
radioligand
Online Access:https://www.mdpi.com/1422-0067/20/3/563

Internet

https://www.mdpi.com/1422-0067/20/3/563

Similar Items