Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis

Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis

Abstract Background Transcription factor forkhead box M1 (FOXM1) is a crucial regulator in colorectal cancer (CRC) progression. However, the regulatory mechanisms causing dysregulation of FOXM1 in CRC remain unclear. Methods Dual-luciferase reporter assay was conducted to determine FOXM1 as miR-6868...

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Bibliographic Details
Main Authors: Ye Wang, Meijuan Wu, Zengjie Lei, Mengxi Huang, Zhiping Li, Liya Wang, Qijun Cao, Dong Han, Yue Chang, Yanyan Chen, Xiaobei Liu, Lijun Xue, Xiaobei Mao, Jian Geng, Yanan Chen, Tingting Dai, Lili Ren, Qian Wang, Hongju Yu, Cheng Chen, Xiaoyuan Chu
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
FOXM1
miRNA
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s13046-018-0970-5

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http://link.springer.com/article/10.1186/s13046-018-0970-5

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