Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype

The DNA mismatch repair (MMR) pathway corrects specific types of DNA replication errors that affect microsatellites and thus is critical for maintaining genomic integrity. The genes of the MMR pathway are highly conserved across different organisms. Likewise, defective MMR function universally res...

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Bibliographic Details
Main Authors: Hanlee P. Ji, Shannon Morales, Katrina Welch, Cam Yuen, Kyle Farnam, James M Ford
Format: Article
Language:English
Published: Pensoft Publishers 2012-07-01
Series:BioDiscovery
Subjects:
Online Access:https://biodiscovery.pensoft.net/article/8918/download/pdf/