Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype
The DNA mismatch repair (MMR) pathway corrects specific types of DNA replication errors that affect microsatellites and thus is critical for maintaining genomic integrity. The genes of the MMR pathway are highly conserved across different organisms. Likewise, defective MMR function universally res...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Pensoft Publishers
2012-07-01
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Series: | BioDiscovery |
Subjects: | |
Online Access: | https://biodiscovery.pensoft.net/article/8918/download/pdf/ |