Diterpenoids from Azorella compacta (Umbelliferae) active on Trypanosoma cruzi

Diterpenoids from Azorella compacta (Umbelliferae) active on Trypanosoma cruzi

The anti-Trypanosoma cruzi activity of natural products isolated from Azorella compacta was evaluated, with particular emphasis on their effect against intracellular amastigotes. Five diterpenoids from A. compacta derived from mulinane and azorellane were isolated and identified. Only two products,...

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Bibliographic Details
Main Authors: Araya Jorge E, Neira Iván, Silva Solange da, Mortara Renato A, Manque Patricio, Cordero Esteban, Sagua Hernán, Loyola Alberto, Bórquez Jorge, Morales Glauco, González Jorge
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2003-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trypanosoma cruzi
intracellular amastigotes
lysis
diterpenoids
Azorella compacta
chemotherapy
confocal microscopy
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300022

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300022

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