Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.

Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.

The CD1e protein participates in the presentation of lipid antigens in dendritic cells. Its transmembrane precursor is transported to lysosomes where it is cleaved into an active soluble form. In the presence of bafilomycin, which inhibits vacuolar ATPase and consequently the acidification of endoso...

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Bibliographic Details
Main Authors: Catherine Angénieux, François Waharte, Alexandre Gidon, François Signorino-Gelo, Virginie Wurtz, Rim Hojeij, Fabienne Proamer, Christian Gachet, Alain Van Dorsselaer, Daniel Hanau, Jean Salamero, Henri de la Salle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411835?pdf=render

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http://europepmc.org/articles/PMC3411835?pdf=render

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