Harman and norharman, metabolites of the entomopathogenic fungus Conidiobolus coronatus (Entomophthorales), affect the serotonin levels and phagocytic activity of hemocytes, insect immunocompetent cells, in Galleria mellonella (Lepidoptera)

Abstract Background Although the β-carboline alkaloids harman and norharman are considered as plant metabolites, they can also be secreted by fungi such as the entomopathogen Conidiobolus coronatus. Norharman and harman are also known to be reversible competitive monamine oxidase inhibitors, which i...

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Bibliographic Details
Main Authors: Anna Katarzyna Wrońska, Mieczysława Irena Boguś
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-019-0291-1