Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion

Immunity: exhausted T cells provide subtle long-term defenses A type of T cell previously thought to be defective could actually provide long-term mild immune responses for combating cancer. The unique environment created during chronic infections gives rise to functionally inert T cells known as ‘e...

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Bibliographic Details
Main Authors: Wooseok Seo, Chandsultana Jerin, Hiroyoshi Nishikawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-021-00568-0