Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion
Immunity: exhausted T cells provide subtle long-term defenses A type of T cell previously thought to be defective could actually provide long-term mild immune responses for combating cancer. The unique environment created during chronic infections gives rise to functionally inert T cells known as ‘e...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-021-00568-0 |