PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells.

PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells.

Despite significant progress, the molecular mechanisms responsible for pancreatic beta cell depletion and development of diabetes remain poorly defined. At present, there is no preventive measure against diabetes. The positive impact of CXCL12 expression on the pancreatic beta cell prosurvival pheno...

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Bibliographic Details
Main Authors: Jelena Marković, Nevena Grdović, Svetlana Dinić, Teodora Karan-Djurašević, Aleksandra Uskoković, Jelena Arambašić, Mirjana Mihailović, Sonja Pavlović, Goran Poznanović, Melita Vidaković
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608566?pdf=render

Internet

http://europepmc.org/articles/PMC3608566?pdf=render

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