Can Non-steroidal Anti-inflammatory Drugs Affect the Interaction Between Receptor Binding Domain of SARS-COV-2 Spike and the Human ACE2 Receptor? A Computational Biophysical Study

Can Non-steroidal Anti-inflammatory Drugs Affect the Interaction Between Receptor Binding Domain of SARS-COV-2 Spike and the Human ACE2 Receptor? A Computational Biophysical Study

SARS-CoV-2 has caused millions of infections and more than 600,000 deaths worldwide. Despite the large number of studies to date, there is no specifically effective treatment available for SARS-CoV-2. However, it has been proposed to target reused drugs with potential antiviral activity to the inter...

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Bibliographic Details
Main Authors: Lenin A. González-Paz, Carla A. Lossada, Francelys V. Fernández-Materán, J. L. Paz, Joan Vera-Villalobos, Ysaias J. Alvarado
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physics
Subjects:
SARS-COV-2
NSAIDs
molecular docking
molecular dynamics
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2020.587606/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2020.587606/full

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