Polygenic Risk Score for Alzheimer’s Disease Is Associated With Ch4 Volume in Normal Subjects

Polygenic Risk Score for Alzheimer’s Disease Is Associated With Ch4 Volume in Normal Subjects

Alzheimer’s disease (AD) is a common neurodegenerative disease. APOE is the strong genetic risk factor of AD. The existing genome-wide association studies have identified many single nucleotide polymorphisms (SNPs) with minor effects on AD risk and the polygenic risk score (PRS) is presented to comb...

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Bibliographic Details
Main Authors: Tao Wang, Zhifa Han, Yu Yang, Rui Tian, Wenyang Zhou, Peng Ren, Pingping Wang, Jian Zong, Yang Hu, Qinghua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Genetics
Subjects:
Alzheimer’s disease
single nucleotide polymorphisms
polygenic risk score
Ch4 region
APOE
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00519/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00519/full

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