Transplanting supersites of HIV-1 vulnerability.

Transplanting supersites of HIV-1 vulnerability.

One strategy for isolating or eliciting antibodies against a specific target region on the envelope glycoprotein trimer (Env) of the human immunodeficiency virus type 1 (HIV-1) involves the creation of site transplants, which present the target region on a heterologous protein scaffold with preserve...

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Bibliographic Details
Main Authors: Tongqing Zhou, Jiang Zhu, Yongping Yang, Jason Gorman, Gilad Ofek, Sanjay Srivatsan, Aliaksandr Druz, Christopher R Lees, Gabriel Lu, Cinque Soto, Jonathan Stuckey, Dennis R Burton, Wayne C Koff, Mark Connors, Peter D Kwong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084637?pdf=render

Internet

http://europepmc.org/articles/PMC4084637?pdf=render

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