Transplanting supersites of HIV-1 vulnerability.
One strategy for isolating or eliciting antibodies against a specific target region on the envelope glycoprotein trimer (Env) of the human immunodeficiency virus type 1 (HIV-1) involves the creation of site transplants, which present the target region on a heterologous protein scaffold with preserve...
Main Authors: | Tongqing Zhou, Jiang Zhu, Yongping Yang, Jason Gorman, Gilad Ofek, Sanjay Srivatsan, Aliaksandr Druz, Christopher R Lees, Gabriel Lu, Cinque Soto, Jonathan Stuckey, Dennis R Burton, Wayne C Koff, Mark Connors, Peter D Kwong |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4084637?pdf=render |
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