“Janus-Faced” α-Synuclein: Role in Parkinson’s Disease

“Janus-Faced” α-Synuclein: Role in Parkinson’s Disease

Parkinson’s disease (PD) is a pathological condition characterized by the aggregation and the resultant presence of intraneuronal inclusions termed Lewy bodies (LBs) and Lewy neurites which are mainly composed of fibrillar α-synuclein (α-syn) protein. Pathogenic aggregation of α-syn is identified as...

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Bibliographic Details
Main Authors: Bipul Ray, Arehally M. Mahalakshmi, Sunanda Tuladhar, Abid Bhat, Asha Srinivasan, Christophe Pellegrino, Anbarasu Kannan, Srinivasa Rao Bolla, Saravana Babu Chidambaram, Meena Kishore Sakharkar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
α-synuclein
autophagy
neurotoxicity
gut–brain axis
Parkinson’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.673395/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.673395/full

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