Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression

Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved...

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Bibliographic Details
Main Authors: Tsung-Hsien Chen, Shan-Wen Liu, Mei-Ru Chen, Kuan-Hung Cho, Tzu-Yin Chen, Pao-Hsien Chu, Yu-Ying Kao, Ching-Han Hsu, Kurt Ming-Chao Lin
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/539805