Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease

<p><b>Objective:</b> TRAF3 and TRAF5 share a common ancestral gene, and interact as essential components of signaling pathways in immunity. TRAF3 and TRAF5 are overexpressed in the colon of rat/mouse models with colitis. However, the expressions of TRAF3 and TRAF5 in patients with...

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Bibliographic Details
Main Author: Jun Shen, Yu-qi Qiao, Zhi-hua Ran, Tian-rong Wang
Format: Article
Language:English
Published: Ivyspring International Publisher 2013-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v10p0156.htm