Rejuvenated ageing mesenchymal stem cells by stepwise preconditioning ameliorates surgery-induced osteoarthritis in rabbits

Aims: Ageing-related incompetence becomes a major hurdle for the clinical translation of adult stem cells in the treatment of osteoarthritis (OA). This study aims to investigate the effect of stepwise preconditioning on cellular behaviours in human mesenchymal stem cells (hMSCs) from ageing patients...

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Bibliographic Details
Main Authors: Zhixian Zong, Xiaoting Zhang, Zhengmeng Yang, Weihao Yuan, Jianping Huang, Weiping Lin, Ting Chen, Jiahao Yu, Jiming Chen, Liao Cui, Gang Li, Bo Wei, Sien Lin
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2020-12-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.101.BJR-2020-0249.R1